Several factors influence a point spread. It starts with power rankings. The media creates power rankings throughout the year, but those can be entirely subjective based more on feelings and emotions than actual raw data. An oddsmaker creates power rankings based on a host of statistics, some more complex than others. The rankings will include record, strength of schedule, and various offensive, defensive, and special teams metrics. They might use Football Outsiders’ efficiency metrics, they might use expected points added, or they might use a host of other internal and external options. The idea being to develop as objective an assessment as possible as to how good or bad a given team is compared to the rest of the NFL.
You can also bet straight winners and losers -- with no point spreads involved -- with money line wagers. When there is a minus number you bet that amount to win $100 in profit. When there is a plus number, that is your winning profit for every $100 wagered. So if the Cowboys have a money line of -250, you would have to bet $250 on them to win $100 in profit on any Dallas victory. If the Giants had a money line of +150, you would win $150 in profit with a winning $100 bet. If a money line is posted as even, you would win a $100 profit on a $100 winning bet.
It's also important to consider whether or not there's any correlation between the point spread and the betting total. If they are, a parlay wager is a good way to get maximum value. For example, a college football point spread +24.5 parlayed with under 48 points in the same game might be a great parlay bet. If the +24.5 team covers the point spread, then there's an increased chance that the game also goes under the posted total of 48.
In most cases, the favorite will be the team with a negative moneyline (in some cases both teams can have a negative moneyline if they are both closely matched). A line of -160 means that you would have to bet $160 to win your base amount of $100. A team with a moneyline of -130 wouldn't be favored nearly as strongly as a team with a moneyline of -330.
Absolutely. When the lines go up for the NFL, or for the first game of the NCAA men’s basketball tournament, there are several days in between the open and the game itself where movement can take place. You’ll find that the betting public tends to pile in on their favorite teams once they get home from work on Friday. You can anticipate these line movements and time your bet accordingly to take advantage.
Oftentimes a point spread will not be a whole number, and will be accompanied by a decimal point and a half number. This can be significant for a point spread. Essentially what it comes down to is that a whole number point spread gives the opportunity for a wager to push. A push means that if the favorite is favored by 10 points and wins by 10 points, bettors get their money back. Just like when betting on the over/under total for points, the spread is a half-point in addition to the whole number, there is no chance to push.

First and foremost, I would look at the overall offensive rankings of both teams.  Even though the saying is that defense wins championship, offense wins games, and an explosive offense could be the difference between you not only covering the spread, but also hitting the over/under bet.  There is a common belief that sharp sports bettors don’t bet favorites and don’t like offensive juggernauts.  I am here to tell you that is bologna.  Some of our biggest wagers each and every football season will be on a well focused large favorite.  There is no better bet out there than finding an attentive favorite that is ready to pour it on.
As always, beware of sites offering paid or free NFL betting picks in connection with a varying unit betting system. If you are using their pro football betting picks to gamble on NFL football games, you might consider that some of these sites are providing money tips which are likely to drain your NFL sportsbook account. Earning gambling profits long term takes discipline to know there is always another game to bet on. Most free sports pick sites don't understand that it requires more than winning football predictions to earn a living betting on sports. So for anyone living in an area where NFL gambling is legal, keep in mind that relying on "bet the house" free NFL picks could seriously reduce your NFL betting success.
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