Let’s say you decide to bet $100 on the Packers to win by more 7 points and the final score is Packers 30, Seahawks 21.  The Packers have won by 9 points, meaning they’ve covered the spread, and you’ve won the bet. The -110 means that your $100 bet will win you a total of $190. That total includes your original bet amount, so your total profit is $90.
If a team favored by six points wins by exactly six points, the outcome is considered a "push" and the bettors get their money back, minus the bookmaker's commission. To reduce the number of pushes, oddsmakers often set spreads with half-points. So if the Cowboys are 3 1/2- or 3.5-point favorites over the Giants, they must prevail by four or more points to pay winning bets.
--Fractional odds are most commonly found in racing. A 10/1 payout should be read "$10 paid for every $1 wagered." When the bigger number is on the left, you will find that bet is normally an underdog in the race. Also note, however, that in case such as "Who will win the Super Bowl in the NFL?" you will see all the teams listed as "underdogs"… i.e. paying at least 2/1 (some up to 300/1 or more).
The one variance you might come across in any pointspread listing is the commission owed on a bet. Instead of moving the actual spread for a game, some books will try and direct money one way or the other by adjusting the juice. For example, if there was a (-120) next to the listed pointspread, you would now owe $120 on a losing $100 bet. Sometimes a book will reduce or eliminate the juice all together to move money towards a particular side of a matchup. In this case, you might see (-105) or (+100) next to the pointspread to signify the reduced or zero commission for that bet.

Understand that negative odds indicate how much money your must spend to make $100. When betting on the favorite, you take less risk, and thus earn less. When betting on a favorite, the moneyline is the amount of money you need to spend to make $100 profit. In the previous example, in order to make $100 of profit betting for the Cowboys, you would need to spend $135. Like positive odds, you earn back your bet when winning.
As you can see, understanding the -110 in sports betting is pretty basic once you realize what it represents. You can also apply this knowledge to other odds as well, such as the money line. This kind of bet is different because you are betting who will win the game straight-up, which causes the odds to be different for each game (instead of -110 for everything).

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