On December 7, 1980 the San Francisco 49ers overcame a halftime deficit of 28 points in what became the greatest regular season comeback victory in NFL regular season history. By the beginning of the third quarter, notorious Vegas bookmaker Frank Rosenthal received forfeiture notices from 246 San Francisco bettors totaling more than $25,000 in premature winnings. Rosenthal was able to retain these winnings despite the final outcome of the game due to gambling regulations previously established by the NAGRA.
“Limitations. Subject to the foregoing, and subject to all of the terms and conditions of this Compact, the Tribe shall establish, at its discretion, by tribal law, such limitations as it deems appropriate on the amount and type of Class III Gaming conducted, the location of Class III Gaming on Indian Lands, the hours and days of operation, and betting and pot limits, applicable to such gaming.”
In most cases, the favorite will be the team with a negative moneyline (in some cases both teams can have a negative moneyline if they are both closely matched). A line of -160 means that you would have to bet $160 to win your base amount of $100. A team with a moneyline of -130 wouldn't be favored nearly as strongly as a team with a moneyline of -330.
Money Line: More common in baseball and hockey, pro football moneylines are growing in popularity. There is no spread, so your team just needs to win the game, not win by a certain number of points. The negative value means a favorite (-190) and a positive one indicates an underdog (+170). Picture the number 100 sitting in between these two values. Example: if you want to pick a -190 favorite, you must risk $190 in order to win $100. To back a +170 underdog, you put up $100 and win $170 if the dog wins. In some cases, betting moneylines is actually better value and can provide a bigger profit for less risk.